Toxo is a MATLAB library for GWAS dataset simulation. It calculates penetrance tables of epistasis models of any interaction order. Toxo is capable of calculating penetrance tables with extreme values of prevalence and/or heritability, which in turn allows to generate datasets resembling real populations more closely.
MPI3SNP is a GWAS program, written in C++, dedicated to epistasis detection. It implements a three-way exhaustive search for cluster architectures with the aim of mitigating the exponential growth of the runtime. MPI3SNP targets both GPU and CPU clusters.